Lucy W. Barrett, Sue Fletcher, "Untranslated Gene Regions and Other Non-coding Elements: Regulation of Eukaryotic Gene Expression"
2013 | ISBN-10: 3034806787 | 80 pages | PDF | 4,5 MB
2013 | ISBN-10: 3034806787 | 80 pages | PDF | 4,5 MB
There is now compelling evidence that the complexity of higher organisms correlates with the relative amount of non-coding RNA rather than the number of protein-coding genes. Previously dismissed as “junk DNA”, it is the non-coding regions of the genome that are responsible for regulation, facilitating complex temporal and spatial gene expression through the combinatorial effect of numerous mechanisms and interactions working together to fine-tune gene expression.