Survival data or more general time-to-event data occur in many areas, including medicine, biology, engineering, economics, and demography, but previously standard methods have requested that all time variables are univariate and independent. This book extends the field by allowing for multivariate times. Applications where such data appear are survival of twins, survival of married couples and families, time to failure of right and left kidney for diabetic patients, life history data with time to outbreak of disease, complications and death, recurrent episodes of diseases and cross-over studies with time responses. As the field is rather new, the concepts and the possible types of data are described in detail and basic aspects of how dependence can appear in such data is discussed. Four different approaches to the analysis of such data are presented. The multi-state models where a life history is described as the subject moving from state to state is the most classical approach. The Markov models make up an important special case, but it is also described how easily more general models are set up and analyzed. Frailty models, which are random effects models for survival data, made a second approach, extending from the most simple shared frailty models, which are considered in detail, to models with more complicated dependence structures over individuals or over time. Marginal modelling has become a popular approach to evaluate the effect of explanatory factors in the presence of dependence, but without having specified a statistical model for the dependence. Finally, the completely non-parametric approach to bivariate censored survival data is described. This book is aimed at investigators who need to analyze multivariate survival data, but due to its focus on the concepts and the modelling aspects, it is also useful for persons interested in such data, but

During the last two decades, structural equation modeling (SEM) has emerged as a powerful multivariate data analysis tool in social science research settings, especially in the fields of sociology, psychology, and education. Although its roots can be traced back to the first half of this century, when Spearman (1904) developed factor analysis and Wright (1934) introduced path analysis, it was not until the 1970s that the works by Karl Joreskog and his associates (e. g. , Joreskog, 1977; Joreskog and Van Thillo, 1973) began to make general SEM techniques accessible to the social and behavioral science research communities.

This book offers a new, fairly efficient, and robust alternative to analyzing multivariate data. The analysis of data based on multivariate spatial signs and ranks proceeds very much as does a traditional multivariate analysis relying on the assumption of multivariate normality; the regular L2 norm is just replaced by different L1 norms, observation vectors are replaced by spatial signs and ranks, and so on. A unified methodology starting with the simple one-sample multivariate location problem and proceeding to the general multivariate multiple linear regression case is presented.

Scientists and others today often collect samples of curves and other functional observations. This monograph presents many ideas and techniques for such data. Included are expressions in the functional domain of such classics as linear regression, principal components analysis, linear modeling, and canonical correlation analysis, as well as specifically functional techniques such as curve registration and principal differential analysis. Data arising in real applications are used throughout for both motivation and illustration, showing how functional approaches allow us to see new things, especially by exploiting the smoothness of the processes generating the data. The data sets exemplify the wide scope of functional data analysis; they are drawn from growth analysis, meteorology, biomechanics, equine science, economics, and medicine.

There has been a dramatic growth in the development and application of Bayesian inferential methods. Some of this growth is due to the availability of powerful simulation-based algorithms to summarize posterior distributions. There has been also a growing interest in the use of the system R for statistical analyses. R's open source nature, free availability, and large number of contributor packages have made R the software of choice for many statisticians in education and industry.

From basics to advanced level training and practices in doing linear regression analysis using R, SPSS, SAS, Python

Apply linear regression to real time datasets

This book provides a visual and intuitive coverage of the core theory of linear models. Designed to develop fluency with the underlying mathematics and to build a deep understanding of the principles, it's an excellent basis for a one-semester course on statistical theory and linear modeling for intermediate undergraduates or graduate students.

This text is designed for a one-semester course on Probability and Statistics. The exposition unfolds systematically from an introductory chapter to such topics as random variables and vectors, stochastic processes, estimation, testing and regression. The topics are well chosen and the presentation is enriched by many examples from real life.

The contributions collected in this book have been written by well-known statisticians to acknowledge Ludwig Fahrmeir's far-reaching impact on Statistics as a science, while celebrating his 65th birthday. The contributions cover broad areas of contemporary statistical model building, including semiparametric and geoadditive regression, Bayesian inference in complex regression models, time series modelling, statistical regularization, graphical models and stochastic volatility models.