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Follows the lives and families of three adults living and growing up in the United States of America in present and past times. As their paths cross and their life stories intertwine in curious ways, we find that several of them share the same birthday - and so much more than anyone would expect.
The sitcom is centered on five characters living in Pasadena, California: roommates Leonard Hofstadter and Sheldon Cooper; Penny, a waitress and aspiring actress who lives across the hall; and Leonard and Sheldon's equally geeky and socially awkward friends and co-workers, mechanical engineer Howard Wolowitz and astrophysicist Raj Koothrappali. The geekiness and intellect of the four guys is contrasted for comic effect with Penny's social skills and common sense.
CDC researcher Abby Arcane investigates what seems to be a deadly swamp-born virus in a small town in Louisiana but she soon discovers that the swamp holds mystical and terrifying secrets. When unexplainable and chilling horrors emerge from the murky marsh, no one is safe.
The rivalries, romances, hopes and fears of the residents of the fictional Midwestern metropolis, Genoa City. The lives and loves of a wide variety of characters mingle through the generations, dominated by the Newman, Abbott, Baldwin and Winters families.